Long-term ingestion of ammonium inhibits lysosomal proteolysis in rat liver.
نویسندگان
چکیده
A standard diet was supplemented with ammonium acetate (20%, w/w). The effect on liver protein degradation of oral administration of the ammonium diet to rats for 6 weeks has been studied. It is shown that lysosomal proteolysis is markedly decreased (by 62%) while non-lysosomal proteolysis is inhibited by 11%. This is the first report showing that ammonium ingestion inhibits liver proteolysis.
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ورودعنوان ژورنال:
- FEBS letters
دوره 234 1 شماره
صفحات -
تاریخ انتشار 1988